Focal的問題，透過圖書和論文來找解法和答案更準確安心。 我們找到下列懶人包和總整理

Crime Fiction in the Age of #metoo

為了解決Focal的問題，作者Beyer, Charlotte 這樣論述：

Crime Fiction in the Age of #MeToo presents a compelling and timely fourth-wave feminist reading of crime fiction in the age of #metoo. The book explores four major fourth-wave feminist focal points, #metoo, rape culture/reclaim the night, toxic masculinity, and LBGTQ+ perspectives. These topics

have been the subject of intense feminist scrutiny and campaigning, and this attention is reflected in contemporary crime fiction and its generic and thematic preoccupation with such topics.The book opens with a chapter presenting an overview of existing critical perspectives and feminist debates, d

emonstrating how fourth-wave feminist ideas and debates are generating fresh ways of reading past crime texts, and new ways of reading new crime fictions. The chapter also outlines the book’s methodology. Each of the four main chapters examining these issues will use the critical vocabulary and conc

epts from discourses of resistance to present new readings of recently published crime fictions, and to reassess canonical works and authors in order to produce new compelling critiques of gender and genre.Through a focus on actively reading and engaging with crime literature, Crime Fiction in the A

ge of #MeToo will redress this significant gap in knowledge and meet a substantial need in scholarly debates for a fourth-wave feminist analysis of crime fiction which draws links between literature and ongoing urgent social and cultural debates.

Focal進入發燒排行的影片

基於曲電與介電效應之三穩態切換負型膽固醇液晶元件的光電響應

為了解決Focal的問題，作者陳冠然 這樣論述：

本研究於負型液晶DV10001中添加右旋手性分子R5011形成負型膽固醇液晶，接著經由摻雜不同配比濃度之彎曲型液晶分子CB7CB使配製完成之液晶材料具有不同程度的曲電特性，筆者藉此探討負型膽固醇液晶在摻雜彎曲型液晶分子後於不同電場條件下的紋理形成種類以及其光電響應。實驗結果分析中，對於形成紋理之介電頻譜進行首要之探討，透過均勻橫向螺紋態（ULH）紋理於介電實部之曲電鬆弛訊號判斷此材料之曲電特性，接著將其鬆弛強度90%與10%所對應於介電頻譜上之頻率點進行紋理切換頻率區間的劃分，並作為此研究之三穩態紋理切換中操作頻率區間的依據。當操作頻率f < fL，液晶分子因強烈的電流體效應及曲電強度而得以

形成ULH態；在頻率fL < f < fH區間中，曲電特性隨著頻率的增加逐漸變小，漸漸的由介電效應主導，此時液晶分子於電場驅動下形成焦錐態（FC）；當頻率f > fH，此時曲電效應幾乎完全消失，液晶分子受介電效應主導而形成平面態（P）。筆者藉由本研究提供了讀者一套於負型膽固醇液晶達成三穩態紋理切換的分析方法，並透過介電頻譜與光電特性量測詳細地說明其紋理背後的形成機制與應用。

Let Them Rot: Antigone’’s Parallax

為了解決Focal的問題，作者Zupančič, Alenka 這樣論述：

A provocative, highly accessible journey to the heart of Sophocles’ Antigone elucidating why it keeps resurfacing as a central text of Western thought and Western culture.There is probably no classical text that has inspired more interpretation, critical attention, and creative response than Soph

ocles’ Antigone. The general perspective from which the book is written could be summarized with this simple question: What is it about the figure of Antigone that keeps haunting us? Why do all these readings and rewritings keep emerging? To what kind of always contemporary contradiction does the ne

ed, the urge to reread and reimagine Antigone--in all kinds of contexts and languages--correspond? As key anchor points of this general interrogation, three particular ＂obsessions＂ have driven the author’s thinking and writing about Antigone. First is the issue of violence. The violence in Antigone

is the opposite of ＂graphic＂ as we have come to know it in movies and in the media; rather, it is sharp and piercing, it goes straight to the bone. It is the violence of language, the violence of principles, the violence of desire, the violence of subjectivity. Then there is the issue of funerary ri

tes and their role in appeasing the specific ＂undeadness＂ that seems to be the other side of human life, its irreducible undercurrent that death alone cannot end and put to rest. This issue prompted the author to look at the relationship between language, sexuality, death, and ＂second death.＂ The th

ird issue, which constitutes the focal point of the book, is Antigone’s statement that if it were her children or husband lying unburied out there, she would let them rot and not take it upon herself to defy the decree of the state. The author asks, how does this exclusivist, singularizing claim (sh

e would do it only for Polyneices), which she uses to describe the ＂unwritten law＂ she follows, tally with Antigone’s universal appeal and compelling power? Attempting to answer this leads to the question of what this particular (Oedipal) family’s misfortune, of which Antigone chooses to be the guar

dian, shares with the general condition of humanity. Which in turn forces us to confront the seemingly self-evident question: ＂What is incest?＂ Let Them Rot is Alenka Zupančič’s absorbing and succinct guided tour of the philosophical and psychoanalytic issues arising from the Theban trilogy. Her ori

ginal and surprising intervention into the broad and prominent field of study related to Sophocles’ Antigone illuminates the classical text’s ongoing relevance and invites a wide readership to become captivated by its themes.

透過基於基因本體之整合性分析識別卵巢上皮性腫瘤發病機轉的失調基因功能體

為了解決Focal的問題，作者蘇國銘 這樣論述：

上皮性卵巢癌（EOCs）在晚期或復發的婦科惡性腫瘤中常是致命的和頑固的，其中漿液性佔絕大多數而卵巢清亮細胞癌（OCCC）是僅次於漿液性上皮性卵巢癌的第二常見的上皮性卵巢癌。即便經過腫瘤減積手術後加上化學藥物治療後仍有不少的患者有著較差的預後或是復發，故整體而言，對於卵巢癌的治療仍是一個相當大的挑戰。此外，邊緣性卵巢腫瘤(BOT)，包括漿液性 BOT與黏液性BOT，是屬於介於良性與惡性之間的卵巢疾病，雖然大部分的預後不差但是也有與卵巢癌不同的組織病理學特性。本研究使用以基因本體(GO)為基礎加上機器學習輔助運算的綜合分析去探討卵巢清亮細胞癌以及漿液性卵巢腫瘤包含漿液性邊緣性卵巢腫瘤與漿液性卵巢

癌的GEO資料庫中失調的基因體、功能途徑，藉以去識別重要的差異表達基因(DEG)。首先在卵巢清亮細胞癌的整合性分析中，發現無論是早期抑或是晚期，與免疫功能相關尤其是活化補體系統的替代途徑的功能失調在腫瘤發生佔有相當重要的關聯性，而補體C3與補體C5也影響了疾病無惡化存活期(Progression-free survival, PFS)和整體存活率(Overall survival, OS)且免疫染色結果是有意義的。而在漿液性卵巢腫瘤的分析中發現，SRC基因和功能失調的芳烴受體(AHR)結合路徑(Binding pathway)確實影響PFS和OS，而且與上皮細胞間質轉化(Epithelial-

mesenchymal transition, EMT)相關的鋅指蛋白SNAI2在腫瘤發生過程中有重要角色，並顯示出從漿液性 BOT 到卵巢癌有著逐漸上升的影響趨勢。未來，標靶治療可以專注於這些有意義的生物標誌並結合精確監測，以提高治療效果和患者存活率。