tpe縮寫的問題，透過圖書和論文來找解法和答案更準確安心。 我們找到下列懶人包和總整理

利用抗菌胜肽與環境敏感型螢光基團設計與合成可選擇性偵測李斯特菌的螢光探針

為了解決tpe縮寫的問題，作者陳衍禎 這樣論述：

目錄目錄..............................................................................................................................i圖目錄........................................................................................................................iii式目錄.......................................

..................................................................................v縮寫表........................................................................................................................vi摘要..........................................................................................

..................................ix第一章、緒論.............................................................................................................11.1前言....................................................................................................................11.2常見的食源性病原菌..............

..........................................................................21.2.1大腸桿菌(Escherichia coli)....................................................................21.2.2金黃色葡萄球菌(Staphylococcus aureus)..............................................21.2.3沙門氏菌(Salmonella)..........................

..................................................31.2.4李斯特菌(Listeria monocytogenes)........................................................31.3細菌檢測常用的方式........................................................................................41.3.1病原菌培養(plating and culturing).........................

................................41.3.2聚合酶鏈鎖反應(polymerase chain reaction).........................................51.3.3酵素結合免疫吸附分析法(enzyme-linked immunosorbent assay).......51.3.4流式細胞術(Flow cytometric)................................................................61.3.5電化學探針(Electrochemical biosenso

rs)...............................................61.3.6螢光檢測.................................................................................................7第二章、分子設計....................................................................................................112.1環境敏感型螢光分子....................

...................................................................112.1.1 激發態分子內質子轉移型探針..........................................................122.1.2激發態分子內質子轉移型探針在生物成像及病原菌檢測中的應用142.1.3聚集誘導放光型探針...........................................................................182.1.4聚集誘導放光型探針在生物成像及病原菌檢測中

的應用...............192.2抗菌胜肽(AMPs).............................................................................................232.2.1 Leucocin A.............................................................................................242.3探針的設計.....................................................

.................................................29第三章、合成以及測試結果討論...........................................................................313.1 Leucocin A片段的合成...................................................................................313.2 AIE型探針的合成步驟.......................................

............................................32ii3.2.1 Acrylic-TPE的合成..............................................................................323.2.2 Acrylic-TPE之labeling測試...............................................................333.2.3 Maleimide-TPE的合成.....................................

...................................343.2.4 Maleimide-TPE之labeling測試..........................................................343.3 Leu-TPE之基本光物理性質..........................................................................383.4 Leu-TPE對Listeria monocytogenes的檢測與討論......................................

393.5 AIE型探針的結構修改...................................................................................413.6 ESIPT型探針的合成......................................................................................433.6.1 Maleimide-3HF-OMe的合成步驟與討論...........................................433.6.2 Maleimide-3HF

-EG-OMe的合成步驟與討論....................................45結論...........................................................................................................................47第四章、實驗部分...................................................................................................484.1一般敘述....

......................................................................................................484.2合成步驟及光譜數據......................................................................................504.3其他實驗.........................................................................................

.................624.3.1 Leucocin A片段與螢光基團的標訂實驗............................................624.3.2 Leu-TPE之基本光物理性質檢測.......................................................644.3.3 Leu-TPE對L.monocytogenes的檢測..................................................66參考文獻.......................................

............................................................................67附錄、1H NMR及13C NMR光譜...........................................................................78附錄、MALDI-MS光譜........................................................................................104

乳酸桿菌胞外多醣體對皮膚細胞影響之研究

為了解決tpe縮寫的問題，作者張億盈 這樣論述：

乳酸桿菌胞外多醣 (Exopolysaccharides，EPS)，為一種在生長及代謝的過程中產生並且分泌到細胞壁外滲入培養基，形成的一種天然多醣體而這些都是微生物適應環境的產物，在文獻裡能看到多醣體對一些疾病有著調理作用，包括：增強免疫力、抗炎、調理腸胃之作用。但目前研究裡還尚未證實乳酸菌胞外多醣對皮膚細胞有生長與延緩老化之功能。因此本研究將探討乳酸菌胞外多醣體萃取物(ExopolySaccharides，EPS)對皮膚上皮細胞HaCaT與纖維母細胞HS68之影響，觀察細胞型態、基質金屬蛋白酶活性以及細胞生長與延緩細胞老化路徑中的蛋白質之變化。經由實驗上結果得知，EPS隨著濃度增加會促進細

胞生長。也利用免疫染色分析法，發現 EPS 可透過活化粒線體促使抑制凋亡蛋白Bcl-xl、Bcl-2、Mcl-1、p-Bad表現量增加，並使促進凋亡蛋白Bad、Bax表現量下降，同時亦促進STAT-3、Survivin、Ki-67表現量上升。此外EPS亦可活化端粒酶，保持端粒穩定，維持細胞的生長能力。由上述的結果推論EPS對皮膚細胞具有著增生之功能，且粒線體活性及活化端粒酶活性，應用在保養品開發上應極具有著潛力及產業上價值。