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Frightfest Guide to Vampire Movies

為了解決Blood plasma的問題，作者 這樣論述：

For centuries, mankind has been chilled by tales of vampires. A fixture of literature, art, and folk tales, the vampire was a natural early choice for a movie monster at the dawn of cinema and has remained popular ever since as the screen’s most enduring and sexually charged nightmare figure. Wit

hin these bloodstained pages, you’ll discover that vampires of the silver screen are far more complex and diverse than variations on Dracula and other staples like Carmilla and the Countess Elizabeth Bathory. All the icons are here, from Bela Lugosi and Max Schreck’s pioneering fiends to the heyday

of Hammer Films, but that’s just a sanguinary taste of what’s to come as you explore macabre offerings from Hong Kong, India, Italy, France, Germany, and more. Along the way you’ll meet vampire-fighting musclemen, rock ’n’ roll bloodsuckers, plasma-craving infants, creepy canines, and supernatural s

trippers. It’s all served up on a blood-spattered silver platter by author and film historian Nathaniel Thompson, who also delivers a globetrotting introduction to the history and evolution of vampire cinema from the silent era to the modern age of undead heartthrobs and vampire assassins. Sweetenin

g the bloody deal is a foreword by legendary writer and monster expert Kim Newman, who dragged vampire literature into the daylight of the modern age with his Anno Dracula series. Take our hand, if you dare, and accept our invitation to explore the dizzying array of frightening, hilarious, and often

beautiful sights and sounds of the undead on film. Following the success of the previous five editions: The FrightFest Guide to Exploitation Movies, Monster Movies, Ghost Movies, Werewolf Movies and Grindhouse Movies, this is the latest in a series of wide appeal books for both the curious spectato

r and the cult connoisseur.

Blood plasma進入發燒排行的影片

An Integrated Approach For Uncovering Novel DNA Methylation Biomarkers For Non-small Cell Lung Carcinoma

為了解決Blood plasma的問題，作者VAIBHAV KUMAR SUNKARIA 這樣論述：

Introduction - Lung cancer is one of primal and ubiquitous cause of cancer related fatalities in the world. Leading cause of these fatalities is non-small cell lung cancer (NSCLC) with a proportion of 85%. The major subtypes of NSCLC are Lung Adenocarcinoma (LUAD) and Lung Small Cell Carcinoma (LUS

C). Early-stage surgical detection and removal of tumor offers a favorable prognosis and better survival rates. However, a major portion of 75% subjects have stage III/IV at the time of diagnosis and despite advanced major developments in oncology survival rates remain poor. Carcinogens produce wide

spread DNA methylation changes within cells. These changes are characterized by globally hyper or hypo methylated regions around CpG islands, many of these changes occur early in tumorigenesis and are highly prevalent across a tumor type.Structure - This research work took advantage of publicly avai

lable methylation profiling resources and relevant comorbidities for lung cancer patients extracted from meta-analysis of scientific review and journal available at PubMed and CNKI search which were combined systematically to explore effective DNA methylation markers for NSCLC. We also tried to iden

tify common CpG loci between Caucasian, Black and Asian racial groups for identifying ubiquitous candidate genes thoroughly. Statistical analysis and GO ontology were also conducted to explore associated novel biomarkers. These novel findings could facilitate design of accurate diagnostic panel for

practical clinical relevance.Methodology - DNA methylation profiles were extracted from TCGA for 418 LUAD and 370 LUSC tissue samples from patients compared with 32 and 42 non-malignant ones respectively. Standard pipeline was conducted to discover significant differentially methylated sites as prim

ary biomarkers. Secondary biomarkers were extracted by incorporating genes associated with comorbidities from meta-analysis of research articles. Concordant candidates were utilized for NSCLC relevant biomarker candidates. Gene ontology annotations were used to calculate gene-pair distance matrix fo

r all candidate biomarkers. Clustering algorithms were utilized to categorize candidate genes into different functional groups using the gene distance matrix. There were 35 CpG loci identified by comparing TCGA training cohort with GEO testing cohort from these functional groups, and 4 gene-based pa

nel was devised after finding highly discriminatory diagnostic panel through combinatorial validation of each functional cluster.Results – To evaluate the gene panel for NSCLC, the methylation levels of SCT(Secritin), FOXD3(Forkhead Box D3), TRIM58(Tripartite Motif Containing 58) and TAC1(Tachikinin

1) were tested. Individually each gene showed significant methylation difference between LUAD and LUSC training cohort. Combined 4-gene panel AUC, sensitivity/specificity were evaluated with 0.9596, 90.43%/100% in LUAD; 0.949, 86.95%/98.21% in LUSC TCGA training cohort; 0.94, 85.92%/97.37 in GEO 66

836; 0.91,89.17%/100% in GEO 83842 smokers; 0.948, 91.67%/100% in GEO83842 non-smokers independent testing cohort. Our study validates SCT, FOXD3, TRIM58 and TAC1 based gene panel has great potential in early recognition of NSCLC undetermined lung nodules. The findings can yield universally accurate

and robust markers facilitating early diagnosis and rapid severity examination.

Clinical Medicine of the Dog and Cat

為了解決Blood plasma的問題，作者 這樣論述：

Dr. Michael Schaer received his D.V.M. degree from the University of Illinois in 1970. He then went to the Animal Medical Center (AMC) in New York City where he served as an intern and then as a medicine resident between1970-73. After the residency, he remained at the AMC as a staff member in the De

partment of Medicine until 1977. He then joined a private small animal practice in New Jersey until late 1978 at which time he joined the faculty at the University of Florida, College of Veterinary Medicine where he has remained until the present time. He has published several papers and book chapte

rs and he has lectured nationally and internationally. Dr Schaer is also the author of five textbooks: Clinical Medicine of the Dog and Cat - 1st, 2nd, and 3rd editions and Clinical Signs in Small Animal Medicine, 1st and 2nd editions. At the U of F, Dr. Schaer functions mainly as a clinician and a

teacher. His previous UF professional duties included: Professor and Associate Chairman-Department of Small Animal Clinical Sciences, Associate Chief of Staff-Small Animal Hospital, and Service Chief-Small Animal Medicine. Dr. Schaer served as Interim Chair, Department of Comparative, Diagnostic, an

d Population Medicine from February 2017-September 2018. He is currently Professor Emeritus and Adjunct Professor in Emergency and Critical Care Medicine, while still doing active teaching in the classroom and in the critical care unit. Dr. Schaer is board certified in internal medicine (ACVIM) and

emergency and critical care (ACVECC).Dr. Frederic Gaschen is a graduate of the University of Bern, Switzerland. After a few years in mixed practice, he trained as a veterinary internist in North America (Ontario Veterinary College, Canada, and University of Florida, USA). He is a specialist in small

animal internal medicine and a Diplomate of both the American and the European Colleges of Veterinary Internal Medicine (ACVM and ECVIM-CA). After teaching for 15 years at his alma mater, he joined the Louisiana State University (LSU) School of Veterinary Medicine 16 years ago where he is currently

a professor of small animal medicine. Frédéric has a passion for canine and feline gastroenterology. He has directed and published research on chronic enteropathies, digestive motility, and the impact of antibiotics on the gut microbiota in dogs and cats and has authored numerous book chapters on s

mall animal gastroenterology topics. Frédéric loves to share his passion with his students, interns, and residents at LSU and with colleagues at congresses worldwide. He has been actively involved in professional associations for many years and is currently co-chair of the scientific committee of th

e World Small Animal Veterinary Association (WSAVA). He has been a member of the editorial team of Clinical Medicine of the Dog and Cat since the 3rd edition.Dr. Stuart Walton is a graduate of the University of Queensland, Australia. Dr. Walton initially working in mixed practice for several years,

before transitioning into emergency medicine and critical care. He trained as a veterinary internist initially in Brisbane, Australia (Veterinary Specialist Services) before travelling to North America where he completed his residency training in small animal internal medicine at Louisiana State Uni

versity (LSU) in Baton Rouge Louisiana. He is a specialist in small animal internal medicine and a Diplomate of the American College of Veterinary Internal Medicine (ACVM). After his residency, Dr. Walton joined the University of Florida (UF) College of Veterinary Medicine where he is currently a cl

inical assistant professor of small animal medicine. Stuart has a broad range of interests including infectious and inflammatory diseases, immune mediated disease, respiratory disease and extracorporeal blood purification techniques. He has directed and published research on therapeutic plasma excha

nge, oomycete infections, and pancreatitis. Stuart is passionate about the profession and is very involved in the education of students, interns, and residents at UF. Stuart is the newest addition to the editorial team of Clinical Medicine of the Dog and Cat.

運動訓練與停止訓練對中老年人骨骼肌氧合能力與身體功能表現之影響

為了解決Blood plasma的問題，作者杨永 這樣論述：

運動是一種改善中老年人骨骼肌氧合能力、提高肌肉力量並最終影響整體身體功能表現的有效方式。然而，較少的研究評估不同運動類型之間訓練效益的差異。此外，由於中老年人生病、外出旅行與照顧兒童等原因，迫使運動鍛煉的中斷。如何合理安排運動訓練的週期、強度與停訓週期，以促使中老年人在未來再訓練快速恢復以往訓練效益，目前亦尚不清楚。本文以三個研究建構而成。研究I：不同運動訓練模式對中老年人的骨骼肌氧合能力、肌力與身體功能表現的影響。以此探討50歲及以上中老年人進行每週2次為期8週的爆發力、阻力訓練以及心肺訓練在改善中老年人肌肉組織氧合能力、與肌肉力量身體功能效益的差異。我們的研究結果表明：爆發力組在改善下肢

肌力、最大爆發力與肌肉品質方面表現出較佳的效果。心肺組提高了30s坐站測試成績並減少了肌肉耗氧量，從而改善了中老年人在30s坐站測試期間的運動經濟性。年紀較高的肌力組則對於改善平衡能力更加有效。此外，三組運動形式均有效改善了中老年人人敏捷性。研究 Ⅱ：停止訓練對運動訓練後中老年人肌力與身體功能表現的影響：系統性回顧與meta分析。本研究欲探討停止訓練對運動訓練後中老年人肌力與身體功能表現訓練效益維持的影響。我們的研究結果表明：訓練期大於停止運動訓練期是肌力維持的重要因素。若訓練期